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Updated: Jul 16, 2026

Resolving Affinity Purified Protein Complexes by Blue Native PAGE and Protein Correlation Profiling
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Published on: April 1, 2017

Mnd2は,中間プロフェーズ中のアナフェーズ促進複合体の重要なアンタゴニストである

Alexandra M Penkner1, Susanne Prinz, Stefan Ferscha

  • 1Vienna Biocenter II, Max Perutz Laboratories, Department of Chromosome Biology, Vienna, Austria.

Cell
|March 31, 2005
PubMed
まとめ

Mnd2タンパク質は,アナフェーズ促進複合体 (APC ((Ama1)) を調節することによって,メオシス中のセキュリンとSgo1の早期の分解を防ぐ. これは,適切な染色体分離を保証し,ヒト卵細胞におけるアヌプロイド性の予防のための標的を提供することができる.

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