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Updated: Jun 25, 2026

Generation of Genetically Modified Organotypic Skin Cultures Using Devitalized Human Dermis
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Perpは,上皮の完全性にとって不可欠なp63-調節された遺伝子です

Rebecca A Ihrie1, Michelle R Marques, Bichchau T Nguyen

  • 1Division of Radiation and Cancer Biology, Stanford University School of Medicine, Stanford, California 94305, USA.

Cell
|March 31, 2005
PubMed
まとめ

Perpはp63の直接標的であり,層状の上皮細胞の発達に不可欠である. ペルプ欠乏症のマウスは,皮膚に水泡を発症し,ペルプが表 epithelial 粘着と組織の完全性を維持する上で重要な役割を果たしていることを明らかにします.

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