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Updated: Jul 1, 2026

Nuclear Magnetic Resonance Spectroscopy for the Identification of Multiple Phosphorylations of Intrinsically Disordered Proteins
12:47

Nuclear Magnetic Resonance Spectroscopy for the Identification of Multiple Phosphorylations of Intrinsically Disordered Proteins

Published on: December 27, 2016

スキャニングポテンシャルヘアピンデナチュレーションを用いた単一ヌクレオチドポリモルフィズムの認識

Fang Wei1, Chunlai Chen, Lin Zhai

  • 1State Key Laboratory of Molecular Dynamic and Stable Structures, and Department of Chemical Biology, College of Chemistry, Peking University, Beijing 100871, China.

Journal of the American Chemical Society
|April 14, 2005
PubMed
まとめ

スキャニング・ポテンシャル・ヘアピン・デナチュレーション (SPHD) は,シングル・ヌクレオチド・ポリモルフィズム (SNP) の検出に敏感で信頼性の高い方法を提供します. この新しいテクニックは,DNAの融解の可能性を分析することによって不一致を正確に区別し,従来型のアッセイの限界を克服します.

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