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Updated: Jul 19, 2026

Isolation of Labile Multi-protein Complexes by in vivo Controlled Cellular Cross-Linking and Immuno-magnetic Affinity Chromatography
10:50

Isolation of Labile Multi-protein Complexes by in vivo Controlled Cellular Cross-Linking and Immuno-magnetic Affinity Chromatography

Published on: March 9, 2010

オリゴメアタンパク質の動的安定化は,単一のリガンド結合イベントによるものです

R Luke Wiseman1, Steven M Johnson, Matthew S Kelker

  • 1Department of Chemistry, the Department of Molecular Biology, and the Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, BCC 265, La Jolla, California 92037, USA.

Journal of the American Chemical Society
|April 14, 2005
PubMed
まとめ

トランスチレチン (TTR) テトラマーを安定させることで,アミロイド病を予防します. TTRに1つの阻害剤を結合させると,結合部位が1つだけを占有している場合でも,解離と分解を阻止するのに十分です.

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Detection of Heterodimerization of Protein Isoforms Using an in Situ Proximity Ligation Assay

Published on: October 20, 2018

Combining Non-reducing SDS-PAGE Analysis and Chemical Crosslinking to Detect Multimeric Complexes Stabilized by Disulfide Linkages in Mammalian Cells in Culture09:37

Combining Non-reducing SDS-PAGE Analysis and Chemical Crosslinking to Detect Multimeric Complexes Stabilized by Disulfide Linkages in Mammalian Cells in Culture

Published on: May 2, 2019

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