関連する実験動画

Updated: Jul 11, 2026

Visualizing and Quantifying Endonuclease-Based Site-Specific DNA Damage
10:59

Visualizing and Quantifying Endonuclease-Based Site-Specific DNA Damage

Published on: August 21, 2021

早期ヒト腫瘍形成における抗癌バリア候補として,DNA損傷反応

Jirina Bartkova1, Zuzana Horejsí, Karen Koed

  • 1Institute of Cancer Biology and Centre for Genotoxic Stress Research, Danish Cancer Society, Strandboulevarden 49, DK-2100 Copenhagen, Denmark. jb@cancer.dk

Nature
|April 15, 2005
PubMed
まとめ

早期の癌細胞は,腫瘍の成長を防ぐためにDNA損傷反応を活性化します. このATM-Chk2-p53経路の欠陥は,がんの進行とゲノム不安定につながる可能性があります.

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