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Updated: Jul 25, 2026

Site Directed Spin Labeling and EPR Spectroscopic Studies of Pentameric Ligand-Gated Ion Channels
11:19

Site Directed Spin Labeling and EPR Spectroscopic Studies of Pentameric Ligand-Gated Ion Channels

Published on: July 4, 2016

ダイオキシゲン誘発のスピン・ラットのリラクゼーション強化を用いたタンパク質結合界面の決定のためのNMR法

M Sakakura1, S Noba, P A Luchette

  • 1Contribution from the Graduate School of Pharmaceutical Sciences, University of Tokyo, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.

Journal of the American Chemical Society
|April 21, 2005
PubMed
まとめ

研究者らは,酸素をパラマグネティック・プローブとして使って,核磁共鳴 (NMR) によるタンパク質結合インターフェイスを特定した. この方法は,リラクゼーション率を分析することによって結合部位を効率的に検出し,他の技術に対する敏感な代替案を提供します.

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