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Updated: May 20, 2026

Whole Mount in Situ Hybridization of E8.5 to E11.5 Mouse Embryos
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TATA結合タンパク質は,酵母細胞の3つの核RNAポリメラーゼのトランスクリプションに必要なタンパク質です

B P Cormack1, K Struhl

  • 1Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115.

Cell
|May 15, 1992
PubMed
まとめ

イーストのTATA結合タンパク質 (TBP) は,RNAポリメラーゼI,II,IIIを含むすべての核遺伝子転写に不可欠です. TBPを非活性化すると,迅速かつ特異的に転写が停止し,遺伝子発現における直接的な役割が確認される.

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