インスリンは,衰弱したヒト心筋に[Ca2+]i依存および[Ca2+]i独立の陽性イノトロピック効果を引き起こす

Dirk von Lewinski1, Sebastian Bruns, Stefanie Walther

  • 1Abteilung Kardiologie und Pneumologie, Georg-August-Universität Göttingen, Göttingen, Germany.

Circulation
|May 11, 2005
PubMed
まとめ

インスリンは,PI-3-キナーゼ経路を通じて,衰弱した人間の心臓の心臓筋収縮を強化します. これは,カルシウム処理の増加を伴うものであり,心不全の治療に臨床的に関連している可能性があります.

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