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Updated: Jul 17, 2026

In Vitro Analysis of PDZ-dependent CFTR Macromolecular Signaling Complexes
10:05

In Vitro Analysis of PDZ-dependent CFTR Macromolecular Signaling Complexes

Published on: August 13, 2012

窒素性グアニンの脱アミネーションと,インターストランドクロスリンク形成のサイトシン触媒

Rainer Glaser1, Hong Wu, Michael Lewis

  • 1Department of Chemistry, University of Missouri-Columbia, 65211, USA. glaserr@missouri.edu

Journal of the American Chemical Society
|May 19, 2005
PubMed
まとめ

DNAにおけるニトロサティブ・グアニン・デアミネーションは,周囲のDNA環境によって著しく変化します. サイトシンは塩基触媒として作用し,反応経路を切り替えて,自由グアニンと比べて異なる製品につながります. これは,さまざまなDNA損傷製品とクロスリンクを説明します.

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