不妊症の治療のための卵巣刺激による多発性出産
Bart C J M Fauser1, Paul Devroey, Nick S Macklon
1Department of Reproductive Medicine, University Medical Centre, Heidelberglaan 100, 3584 CX Utrecht, Netherlands. b.c.fauser@azu.nl
Lancet (London, England)
|May 25, 2005
まとめ
助産生殖技術 (ART) は妊娠の可能性を高めますが,複数の出産のリスクを高めます. このレビューでは,卵巣過刺激と体外受精 (IVF) によるイアトロゲン性多胎妊娠を減らすための戦略を強調しています.
科学分野:
- 生殖医学は,生殖器医学である.
- 産科・婦人科 産科・婦人科
背景:
- 助産生殖技術 (ART) は,ゲメットの相互作用を最適化することによって受胎を促進することを目的としています.
- 技術には,卵巣過刺激,子宮内受精 (IUI),体外受精 (IVF) が含まれる.
- 現在のARTの実践は,複数の妊娠 (双子,トリプルなど) のリスクを大幅に高めています. ) を実施する.
研究 の 目的:
- イアトロゲン性多胎児の発生率の増加に対する意識を高めるために.
- 現在のARTの実践を牽引する背景とトレンドを見直す.
- 多胎妊娠のリスクを軽減するための戦略を強調する.
主な方法:
- 助産生殖技術に関する既存の文献のレビュー.
- ARTに関連する複数の出生率の動向の分析.
- 多胎妊娠のリスクを減らす方法の特定と議論.
主要な成果:
- 先進社会では,多胎児の有意な増加が見られ,その多くはARTによるものである.
- 卵巣過刺激と複数の胚移植は,この増加に主な貢献者である.
- このレビューは,現在の複数出産の流行のイアトロゲン性の性質を強調しています.
結論:
- ARTは,生育に有益ですが,陽性多発妊娠を防ぐために慎重に管理する必要があります.
- 多胎妊娠率を減らすための戦略は,母と乳児の健康にとって極めて重要です.
- 複数出産の流行を食い止めるために,さらなる研究と臨床的調整が必要である.
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