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Updated: Jul 5, 2026

Simultaneous Measurement of Superoxide/Hydrogen Peroxide and NADH Production by Flavin-containing Mitochondrial Dehydrogenases
08:57

Simultaneous Measurement of Superoxide/Hydrogen Peroxide and NADH Production by Flavin-containing Mitochondrial Dehydrogenases

Published on: February 24, 2018

低酸素誘導因子を抑制する因子の選択的阻害

Michael A McDonough1, Luke A McNeill, Melanie Tilliet

  • 1The Department of Chemistry and The Oxford Centre for Molecular Sciences, Chemistry Research Laboratory, University of Oxford, Mansfield Road, Oxford, OX1 3TA, United Kingdom.

Journal of the American Chemical Society
|May 26, 2005
PubMed
まとめ

研究者らは,低酸素誘導因子アスパラギニルヒドロキシラーゼ (FIH) の選択的阻害剤であるN-オクサリル-d-フェニラララニンを発見した. この発見は,治療用遺伝子上位調節のための低酸素反応を調節するのに役立ちます.

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