酸化窒素とシトクロームc'の相互作用と,グアニラートサイクラゼとの関連性. 鉄のヒスティジン結合はなぜ断ち切られるのか?

Marcelo A Martí1, Luciana Capece, Alejandro Crespo

  • 1Departamento de Química Inorgánica, Analítica y Química Física/INQUIMAE-CONICET, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Ciudad Universitaria, Pabellón II, Buenos Aires, Argentina.

まとめ

酸化窒素 (NO) は,鉄-ヒスティジンの結合を裂き,溶性ガニラートサイクラーズ (sGC) を活性化します. この研究では,サイトクロームcのシミュレーションを使用しています.

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