異なるリードコンフィギュレーションで与えられた2つの連続した二相ショックのパルス分離が,心室除細動の有効性に与える影響
E E Johnson1, C A Alferness, P D Wolf
1Department of Medicine, Duke University Medical Center, Durham, N.C.
Circulation
|June 1, 1992
まとめ
連続した二相性ショックの間の間隔を最適化することは,除細動に不可欠です. ≤10 msまたは75125 msの間隔は有効性を改善し,50 msは除細動の値を増やす.
科学分野:
- 心血管科学の研究について
- 電気生理学 電気生理学
- 医療機器 医療機器について
背景:
- 連続した二相ショックは,単発ショックよりもデフィブリレーションの有効性を高めます.
- ショック間隔がデフィブリレーションに与える影響は,研究が必要である.
研究 の 目的:
- 連続した二相性ショックの最適なインターショック間隔を決定する.
- 衝撃の遅延が,除細動の値と成功率にどのように影響するかを評価する.
主な方法:
- デフィブリレーションの値 (DFT) は,さまざまなショック間隔 (0.2125 ms) を有する犬で測定されました.
- リードの構成には,右心室頂部から左側胸部,そして左心室頂部から右心室外流管が含まれていました.
- デフィブリレーション成功確率曲線は,DFTの発見を確認するために生成されました.
主要な成果:
- 平均DFTは,単発衝撃の値よりも10 ms以下の間隔または75125 ms (p = 0.002) の間隔で低かった.
- 50ミリ秒の間隔で,DFTが27Jに大幅に上昇しました.
- 最低エネルギー要求の最適な間隔は0.2msであり,アクティベーション間隔の90%でした.
結論:
- 連続した二相性ショックの最適なインターショックの間隔は,≤10 msまたは75125 msです.
- 50ミリ秒の間隔は,再発性フィブリレーションを誘発し,より強い第二のショックを必要とします.
- タイミングは,連続的なショックでデフィブリレーションの成功を最大化するために重要です.
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