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Updated: May 1, 2026

In Vitro SUMOylation Assay to Study SUMO E3 Ligase Activity
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SUMO-RanGAP1-Ubc9-Nup358複合体によって明らかにされたE3リゲーゼ活性に関する洞察

David Reverter1, Christopher D Lima

  • 1Structural Biology Program, Sloan-Kettering Institute, New York, New York 10021, USA.

Nature
|June 3, 2005
PubMed
まとめ

小型ユビキチン関連変容体 (SUMO) 結合は,重要な細胞過程を調節する. この研究は,SUMOylation複合体の結晶構造を明らかにし,Nup358/RanBP2がUbc9.9経由でSUMO-1結合を強化する方法を示しています.

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