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インタールイキン-1受容体抗体欠乏性マウスにおける弾性血管動脈炎は,エフェクターTh1細胞を関与させ,インタールイキン-1受容体受容体を必要とします

Joanna Shepherd1, Martin J H Nicklin

  • 1Division of Genomic Medicine, University of Sheffield, Sheffield, United Kingdom.

Circulation
|June 9, 2005
PubMed
まとめ

インタールイキン-1受容体アンタゴニスト (IL-1ra) が欠けているマウスは,インタールイキン-1受容体とTh1細胞によって媒介される動脈炎を発症します. このマウスモデルは,人間の弾性血管動脈炎と類似性を示しています.

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