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アポリポプロテインEと慢性腎臓病の進行

Charles C Hsu1, W H Linda Kao, Josef Coresh

  • 1Department of Epidemiology, The Welch Center for Prevention, Epidemiology, and Clinical Research, The Johns Hopkins Medical Institutions, Baltimore, MD 21205-2223, USA.

JAMA
|June 16, 2005
PubMed
まとめ

アポリポプロテインE (APOE) の遺伝子変異は慢性腎臓病 (CKD) の進行に影響を与えます. エプシロン4アレルはリスクを下げ,エプシロン2は他の要因とは無関係にリスクを高めました. これは,CKDにおける非脂質経路を強調しています.

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