反応バイアスの補完的なプロセスは,タラマスの中央核の中央核にある

Takafumi Minamimoto¹, Yukiko Hori, Minoru Kimura

¹Department of Physiology, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan.

Science (New York, N.Y.)

|June 18, 2005

まとめ

報酬を期待するときに脳の活動が増加しますが,予期せぬ,望ましくない行動が求められるとき,決定のバイアスを補完して,中枢タラマス (CM) が重要な役割を果たします.

科学分野:

神経科学は神経科学である.
意思決定研究意思決定
認知神経科学は,認知神経科学である.

背景:

報酬の予期中に特定の領域の脳活動が増加し,意思決定と行動バイアスに影響を与えます.
現実のシナリオでは,しばしば予期せぬ出来事が起こり,望ましい行動と望ましくない行動の選択が必要になる.

研究の目的:

報酬の予期にもかかわらず,望ましくない行動を要求する状況において,中央中部タラマス (CM) の役割を調査する.
意思決定と行動バイアスを補完する神経メカニズムを理解する.

主な方法:

猿の中央中部 (CM) のタラムスのニューロン活動が記録された.
CMの電気刺激を使用して,パフォーマンスへの影響を観察しました.

主要な成果:

CMニューロンの半分以上は,小さな報酬のアクションが必要ですが,大きな報酬のオプションが予想されているときに活性化します.
CMの電気刺激はパフォーマンスを低下させ,活発なアクションを鈍いものに変更しました.

結論:

中心タラマス (CM) は,意思決定と行動バイアスを補完する神経機構に関与しています.
CMは,期待される報酬が,必要な行動と衝突する状況でのナビゲーションに極めて重要です.

さらに関連する動画

09:09

Electrophysiological Investigations of Retinogeniculate and Corticogeniculate Synapse Function

Published on: August 7, 2019

10:08

Microtransplantation of Synaptic Membranes to Reactivate Human Synaptic Receptors for Functional Studies

Published on: July 20, 2022

関連する概念動画

01:23

Atomic Nuclei: Nuclear Relaxation Processes

In the absence of an external magnetic field, nuclear spin states are degenerate and randomly oriented. When a magnetic field is applied, the spins begin to precess and orient themselves along (lower energy) or against (higher energy) the direction of the field. At equilibrium, a slight excess population of spins exists in the lower energy state. Because the direction of the magnetic field is fixed as the z-axis, the precessing magnetic moments are randomly oriented around the z-axis. This...

01:27

Feedback Regulation of Calcium Concentration

Calcium is an essential signaling molecule required for various cellular functions. Calcium pumps and ion channels on cell and organellar membranes, such as those on the endoplasmic reticulum (ER), regulate calcium concentrations inside the cell. They remain closed, keeping the cytosolic calcium levels low at a resting state.
Various transmembrane receptors, such as G protein-coupled receptors (GPCRs), elicit a response to extracellular signals by increasing cytosolic calcium. Activated GPCRs...

01:15

Insensitive Nuclei Enhanced by Polarization Transfer (INEPT)

Insensitive Nuclei Enhanced by Polarization Transfer (INEPT) is an advanced Nuclear Magnetic Resonance (NMR) technique specifically designed to detect and enhance the signals of low-abundance nuclei, such as carbon-13 and nitrogen-15, in small molecules. The fundamental principle behind INEPT is the transfer of polarization from a more abundant and highly polarizable nucleus, typically hydrogen-1, to the low-abundance nucleus of interest. This process effectively boosts the NMR signal of the...

01:30

Diencephalon: Anatomical Regions

The diencephalon, etymologically translated as 'through brain,' plays an integral role as the conduit between the cerebrum and the vast extent of the nervous system. However, the olfactory system is an exception, as it interfaces directly with the cerebrum. The diencephalon, deeply ensconced beneath the cerebrum, primarily consists of three paired structures — the thalamus, hypothalamus, and epithelamus. It also includes accessory structures such as the subthalamus, which houses the subthalamic...

01:27

Diencephalon: Thalamus and Information Relay

The thalamus, often called “the gateway to the cerebral cortex,” is vital in processing and directing sensory and motor signals throughout the brain. Almost all inputs destined for the cerebral cortex, except for olfactory signals, are relayed through the thalamus. The thalamus is a sophisticated relay station, channeling information from various brain regions to the cerebral cortex, as well as a filter, prioritizing certain signals over others based on current physiological states or needs.

01:23

Diencephalon: Hypothalamus and Coordination

The hypothalamus is a small yet highly complex and essential brain region that plays a crucial role in regulating various bodily functions. Anatomically, it is located at the base of the brain, just above the brainstem and below the thalamus, forming part of the limbic system.
The hypothalamus interacts with other brain regions, including the pituitary gland, through a direct physical connection called the hypothalamic-pituitary axis. The hypothalamus receives somatic and visceral inputs and...

関連する実験動画