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肥満は冠動脈バイパス手術における死亡のリスク要因ですか?
Ruyun Jin1, Gary L Grunkemeier, Anthony P Furnary
1Providence Health System, Portland, Ore, USA. Ruyun.Jin@providence.org
Circulation
|June 22, 2005
まとめ
ボディ・マス・インデックス (BMI) は,冠動脈バイパス・グラフティング (CABG) 手術後の死亡の重要な危険因子ではありません. しかし,正常から過体重のBMIが高い患者は,最も低い死亡率を経験しました.
科学分野:
- 心血管外科手術についてです.
- 肥満に関する研究
- 臨床リスク評価 臨床リスク評価
背景:
- 冠動脈バイパス移植 (CABG) 手術後の死亡率に対するボディ・マス・インデックス (BMI) の影響について,矛盾する証拠が存在する.
- 以前の研究では,肥満がCABG患者における入院死亡率の重要なリスク要因であるかどうかについて矛盾した結果が得られた.
研究 の 目的:
- 冠動脈バイパス移植 (CABG) を受けている患者の体質指数 (BMI) と入院死亡率との関係を調査する.
- CABGの手術結果を予測する上で,肥満を含むさまざまなBMIカテゴリーの役割を明確にする.
主な方法:
- 1997年から2003年の間に単離CABGを受けた患者16,218人の大きなコホートの分析.
- 病院での死亡率に対するBMIの影響を評価するために,ロジスティック回帰と分数多項式変換を使用しました.
- 様々なBMIグループにおける死亡率の傾向を特定するために,累積和法を使用した.
主要な成果:
- ボディ・マス・インデックス (BMI) は,さまざまな評価方法において,入院死亡率の統計的に有意な予測因子ではないことが判明しました.
- 累積総分析により,高正常および過体重BMIカテゴリーの患者は,リスク調整による死亡率が最も低いことが明らかになった.
- BMI値が高正常範囲以下または超重量カテゴリーを超える患者では,死亡率のわずかに増加が観察されました.
結論:
- BMIで測定される全身のサイズは,CABG手術後の死亡リスクの有意な要因ではありません.
- 病院での死亡率が最も低いのは,正常なBMIが高く,肥満BMIのサブグループで観察されました.
- 体重不足および肥満の患者は,最適なBMI範囲と比較して,わずかに高い死亡率の傾向を示しました.
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