Search research articles

お問い合わせ

JoVEについて

概要リーダーシップブログ JoVEヘルプセンター

著者向け

出版プロセス編集委員会範囲と方針査読よくある質問投稿

図書館員向け

推薦の声購読アクセスリソース図書館諮問委員会よくある質問

研究

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments アーカイブ

教育

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual 教員リソースセンター教員サイト

プライバシーポリシー

関連する概念動画

Regulation of Hormone Secretion

Regulation of Hormone Secretion

Regulation of hormone secretion is a finely tuned orchestration driven by various types of stimuli, encompassing neural, humoral, and hormonal signals. Environmental cues instigate neural stimuli, where action potentials traverse nerve fibers to reach their designated targets. An illustrative scenario is the body's response to stress, wherein the sympathetic nervous system releases epinephrine from the adrenal glands, inducing the well-known 'fight or flight' reaction.
Humoral...

Hormonal Regulation

Hormonal Regulation

Hormones regulate a significant portion of digestion through activation of the neuroendocrine system. The neuroendocrine system of digestion contains many different hormones all with multiple functions that are both, directly and indirectly, involved in digestion.

Overview of Secretory Vesicles

Overview of Secretory Vesicles

Secretory vesicles, also known as dense core vesicles (DCVs), are membrane-bound vesicles that transport secretory proteins, such as hormones or neurotransmitters. Regulated secretory vesicles transport proteins from the trans-Golgi network to the exterior of the cell. Proteins present in regulated secretory vesicles are required to be rapidly exocytosed in large amounts upon a specific stimulus.
Various proteins regulate the aggregation of molecules inside the secretory vesicles. Chromogranins...

Insulin Secretory Vesicles

Insulin Secretory Vesicles

Insulin secretory vesicles release insulin to stimulate blood glucose uptake and regulate carbohydrate metabolism. When the blood glucose levels increase, glucose enters the pancreatic β-islet cells through glucose transporters. Once inside, glucose is metabolized through glycolysis, the citric acid cycle, and the electron transport chain, producing ATP. This increase in ATP concentration closes ATP-sensitive potassium channels, leading to depolarization of the membrane and the opening of...

Glucose Homeostasis: Pancreatic Islets and Insulin Secretion

Glucose Homeostasis: Pancreatic Islets and Insulin Secretion

The pancreatic islets comprising only 1%-2% of the volume are highly vascularized and innervated mini-organs. They contain five endocrine cell types, including β cells that secrete insulin, which is synthesized as a single polypeptide chain, preproinsulin, processed to proinsulin, and finally to insulin and C-peptide. This process is complex and regulated, involving the Golgi complex, the endoplasmic reticulum, and the secretory granules of the β cell.
Insulin and C-peptide are...

Feedback Inhibition

Feedback Inhibition

Biochemical reactions are occurring constantly in cells, converting starting substances to different products, usually with the help of enzymes that speed the reactions. Without enzymes, it would take far too long for most reactions to occur to be useful to the cell!

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え

Same author

Cation-driven envelope dynamics modulate outer membrane vesiculation and extracellular electron transfer in Geobacter.

Nature communications·2026

Same author

Extracellular electron transfer: From early life to modern biogeochemistry and applications.

Advances in microbial physiology·2026

Same author

Evolution for enhanced extracellular electron transfer in <i>Geobacter sulfurreducens</i> over seventeen years of continuous current generation.

Frontiers in microbiology·2026

Same author

Fe(III) Oxide Reduction Bypassing Outer-Surface Cytochromes in a Marine Respiratory Anaerobe.

Environmental science & technology·2026

Same author

Preemptive biofilm colonization blocks microbial metal corrosion.

NPJ biofilms and microbiomes·2026

Same author

Electroactive Microbes Short-Circuit the Passive Film to Corrode Stainless Steel.

Research (Washington, D.C.)·2026

Search research articles

関連する実験動画

Updated: Jan 10, 2026

Regulation of Hormone Secretion

Regulation of Hormone Secretion

微生物のナノワイヤを介して細胞外電子伝送が行われます.

Gemma Reguera¹, Kevin D McCarthy, Teena Mehta

¹Department of Microbiology, University of Massachusetts, Amherst, Massachusetts 01003, USA.

|June 24, 2005

まとめ

Geobacter sulfurreducens piliは,生物学的ナノワイヤとして作用し,電子を微生物の呼吸のためにFe (III) オキシドに転送します. この発見は,細胞外電子伝達の新しいメカニズムと,バイオエンジニアリングによる伝導性材料の潜在性を明らかにしています.

科学分野:

微生物学微生物学とは
地質化学地質化学
バイオフィジックス生物物理学

背景:

細胞外電子伝達は,微生物の有機物質の分解と栄養素の循環に不可欠です.
外膜C型シトクロームは,微生物によるFe (Fe) の減少の主要な焦点となっている.
ゲオバクテリアの種のようなFe (Fe) を減少させる微生物の中には,c-サイトクロームが欠けていて,代替的な電子伝送メカニズムが必要になる.

研究の目的:

Geobacter sulfurreducensのFe (III) オキシドへの細胞外電子移転におけるピリの役割を調査する.
ゲオバクテリアの種におけるFe (III) オキシドの減少にピリが不可欠であるかどうかを判断する.
Geobacter sulfurreducens pili.の伝導性特性を調査するために.

主な方法:

Geobacter sulfurreducens.のピルス欠乏変異体の構築と分析
野生型および変異株におけるFe (Fe) オキシード還元能力の評価.
伝導探査機原子力顕微鏡を用いて,ピリ伝導性を評価する.

主要な成果:

Geobacter sulfurreducensのピルス欠乏変異体は,Fe (III) オキシドを還元する能力を失った.

さらに関連する動画

Hormonal Regulation of Digestion

Hormonal Regulation of Digestion

Overview of Secretory Vesicles

Overview of Secretory Vesicles

関連する実験動画

Last Updated: Jan 10, 2026

Regulation of Hormone Secretion

Regulation of Hormone Secretion

Hormonal Regulation of Digestion

Hormonal Regulation of Digestion

Overview of Secretory Vesicles

Overview of Secretory Vesicles

変異株は,Fe (III) オキシドに結合する能力を保持しており,ピリは粘着のためだけではないことを示しています.

伝導探査機原子力顕微鏡では,ピリが非常に伝導性が高いことが示されました.

結論:

Geobacter sulfurreducens piliは,生物学的ナノワイヤーとして機能し,細胞から細胞外Fe (III) オキシドへの電子の転送を促進します.
ピリ媒介の電子伝達は,微生物の呼吸と生地化学の循環のための新しいメカニズムを表しています.
ピリの伝導性性質は,新しい伝導性バイオマテリアルをバイオエンジニアリングし,ユニークな細胞表面相互作用を理解するための道を開きます.