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Updated: May 16, 2026

Screening for Melanoma Modifiers using a Zebrafish Autochthonous Tumor Model
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統合的ゲノム解析は,MITFを悪性メラノーマで増幅された系統生存腫瘍遺伝子として特定しています

Levi A Garraway1, Hans R Widlund, Mark A Rubin

  • 1Department of Medical Oncology, and Melanoma Program in Medical Oncology, Dana-Farber Cancer Institute, 44 Binney Street, Boston, Massachusetts 02115, USA.

Nature
|July 8, 2005
PubMed
まとめ

マイクロフタルミア関連転写因子 (MITF) の増幅はメラノーマの進行を促し,患者の生存率を低下させます. MITFをターゲットにすることは,この化学療法に抵抗するがんに対する潜在的な治療戦略を提供します.

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