関連する実験動画
Updated: Aug 8, 2026

11:20
Fabrication and Visualization of Capillary Bridges in Slit Pore Geometry
Published on: January 9, 2014
毛細な分子ネットワークにおけるサブマキシマルの相互貫通と二連続の三次元チャンネル
Okba Saied1, Thierry Maris, Xin Wang
1Département de Chimie, Université de Montréal, Montréal, Québec H3C 3J7, Canada.
Journal of the American Chemical Society
|July 14, 2005
まとめ
テトラレソルシノール1結晶化により,交互に浸透したダイアモンド状のネットワークが生じる. 溶媒の選択はネットワークの相互浸透を決定し,ゲストのアクセシビリティに影響を与え,複雑な物質構造をモデル化します.
科学分野:
- クリスタル・エンジニアリング (Crystal Engineering) とは
- 超分子化学 超分子化学
- マテリアルサイエンス 材料科学
背景:
- テトラキス ((3,5-ディヒドロキシフェニル) シラン (1) は,複雑な水素結合ネットワークを形成する.
- 溶媒の相互作用は,結晶パッキングとネットワークトポロジーに大きな影響を与えます.
研究 の 目的:
- テトラキス (3,5-ジヒドロキシフェニル) シラン (1) の結晶化に対する溶媒の効果を調査する.
- その結果,交互に浸透したダイアモンド状のネットワーク構造とそのゲストを含む性質を特徴づける.
主な方法:
- 単一結晶X線微分分析. 単一結晶X線微分分析. 単一結晶X線微分分析. 単一結晶X線微分分析. 単一結晶X線微分分析. 単一結晶X線微分分析. 単一結晶X線微分分析.
- 溶媒媒介結晶化実験. 溶媒媒介結晶化実験.
主要な成果:
- ヘクサン/メチルプロピオラートからの結晶化により,ゲストを含まない5重の相互浸透ネットワークが生じた.
- ヘクサンからエチルアクリレート,エチルアセテート,THF,またはダイオキソランによる結晶化により,最大3倍の相互浸透性が得られ,ゲストがアクセスできる容量の約50%が得られました.
- ゲスト分子 (THF,ダイオキソラン) は,サブマキシマルの交互に浸透したダイアモンド状構造内の特定のチャネルを占有しました.
結論:
- 溶媒の選択は,テトラレソルシノール1結晶のネットワーク相互浸透の程度を制御する上で極めて重要です.
- サブマキシマルの相互浸透構造は,ブロックコポリマーとアンフィフィリックアセンブリにおける複雑なトポロジーのモデルとして機能する.
- この研究は,可調のゲストアクセシビリティを持つ多孔質の材料を作成するための結晶工学の可能性を強調しています.
関連する概念動画
Gap Junctions
Multicellular organisms employ a variety of ways for cells to communicate with each other. Gap junctions are specialized proteins that form pores between neighboring cells in animals, connecting the cytoplasm between the two, and allowing for the exchange of molecules and ions. They are found in a wide range of invertebrate and vertebrate species, mediate numerous functions including cell differentiation and development, and are associated with numerous human diseases, including cardiac and...
Aquaporins
Aquaporins or AQPs are a family of integral membrane proteins whose primary function is to transport water, while some called aquaglyceroporins also transport glycerol. In addition, aquaporins have also been suspected to be involved in transporting volatile substances, such as carbon dioxide and ammonia, across membranes. Such AQPs that act as gas channels are often highly expressed in cells involved in the gaseous exchange, such as red blood cells, epithelial cells, and pulmonary capillaries.
Multi-pass Transmembrane Proteins and β-barrels
In multi-pass transmembrane proteins, the polypeptide chain crosses the membrane more than once. The transmembrane polypeptide chain either forms an α-helix or β-strand structure. α-Helix containing multi-pass transmembrane proteins are ubiquitous, whereas β-strand containing ones are mainly found in gram-negative bacteria, mitochondria, and chloroplasts.
α-Helix containing multi-pass transmembrane proteins
Multi-pass transmembrane proteins such as G-protein-linked receptors (GPCRs) and...
α-Helix containing multi-pass transmembrane proteins
Multi-pass transmembrane proteins such as G-protein-linked receptors (GPCRs) and...
Structure of Porins
Mitochondria, chloroplasts, and gram-negative bacteria have transmembrane, beta-barrel proteins called porins to mediate the free diffusion of ions and metabolites across the membrane. Mitochondrial porin precursors contain conserved amino acid sequences called beta signals at their C-terminal. Beta signals have a motif of PoXGXXHyXHy (Po-Polar, X-Any amino acid, G-Glycine, Hy-LargeHydrophobic), which are crucial for precursor recognition to initiate precursor assembly. Beta-barrel precursors...
Tight Junctions
Tight junctions are molecular seals between cells that prevent the leaking of fluids, ions, and other small solutes across cavities and compartments in multicellular organisms. They are mainly composed of claudin and occludin transmembrane proteins, and other proteins such as tricellulin and JAM (junctional adhesion molecule). All these proteins are 4-pass transmembrane proteins, except JAM, which is a single-pass transmembrane protein belonging to the immunoglobulin superfamily. The...
Gap Junctions
The cytoplasm of adjacent animal cells can exchange small molecules, ions, and secondary messengers via the communication channels which form the gap junctions. These junctions comprise a few hundred to thousands of molecular channels, each made of two halves, called the connexon hemichannel. A connexon is a hexamer of six transmembrane connexin proteins, which assemble radially, thus forming a pore or channel in the center. One connexon hemichannel docks with a corresponding connexon on the...

