喫煙が世界および地域における心血管疾患による死亡率における役割
Majid Ezzati1, S Jane Henley, Michael J Thun
1Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA. mezzati@hsph.harvard.edu
Circulation
|July 20, 2005
まとめ
喫煙は2000年に世界中で160万人以上の心血管疾患による死亡を引き起こし,すべての心血管疾患による死亡の11%を占めました. これは,世界中の心臓病死亡率の主な予防可能なリスク因子として喫煙を強調しています.
科学分野:
- エピデミオロジー エピデミオロジー
- 公衆衛生は公衆衛生である.
- 心血管疾患に関する研究
背景:
- 喫煙は,世界的に心臓血管疾患 (CVD) 死亡率の主な要因である.
- 喫煙がCVDの死亡率に与える特定の寄与に関するデータは,リスク要因が異なる世界の様々な地域において限られている.
研究 の 目的:
- 世界中で主要な心血管疾患 (心筋梗塞性疾患,脳血管疾患) による喫煙による死亡数を定量化するために.
- これらの死亡を年齢,性別,地域によって分析し,他のリスク要因を調整する.
主な方法:
- アメリカがん協会のがん予防研究II (CPS II) とWHOの疾病による死亡率データベースのデータを活用した.
- 全世界の14のサブリージョンにおける喫煙による死亡率の推定,喫煙暴露のプロキシとして肺がんによる死亡率を用いる.
- CPS-IIデータにおける主要な共変数で調整された.
主要な成果:
- 2000年,喫煙は,世界中で推定162万人の心血管疾患による死亡 (11%のCVD死亡) に寄与した.
- 喫煙による心血管疾患による死亡率は,女性 (45万人) よりも男性 (1.170万人) により高かった.
- 発血性心臓病 (54%) と脳血管疾患 (25%) は,喫煙によるCVD死亡率の主な原因でした.
結論:
- 2000年の世界の心臓血管疾患による死亡の10%以上は,喫煙に関連していた.
- 喫煙は,世界中で心臓血管疾患による死亡の重要な原因であり,予防可能である.
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