ジョージ3世とポルフィリア: 基本的仮説と調査
Timothy M Cox1, Nicola Jack, Simon Lofthouse
1Department of Medicine, University of Cambridge Addenbrooke's Hospital, Cambridge, UK.
Lancet (London, England)
|July 26, 2005
まとめ
ジョージ3世王の歴史上の狂気発作は,急性遺伝性ポルフィリアによるものだけではなかったかもしれない. 彼の髪の毛を分析したところ,高濃度のヒ素が検出され,彼の医療処置による潜在的貢献要因が示唆された.
科学分野:
- バイオケミストリー バイオケミストリー
- 遺伝学 遺伝学とは
- 医学の歴史 医学の歴史
背景:
- ジョージ3世王のエピソード性狂気を急性遺伝性ポルフィリア (バリゲートポルフィリア) と歴史的に診断したのは,限られた証拠に基づいていた.
- 以前の理論では,ヨーロッパの王室との遺伝的関連が示唆されていたが,確固たる証拠は得られなかった.
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