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Updated: Jul 20, 2026

Analyzing Murine Schwann Cell Development Along Growing Axons
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ラスグアニンヌクレオチド交換因子の神経成長因子刺激とGAP活動

B Q Li1, D Kaplan, H F Kung

  • 1Biological Carcinogenesis and Development Program, Program Resources, Inc./DynCorp, Frederick, MD 21702.

Science (New York, N.Y.)
|June 5, 1992
PubMed
まとめ

神経成長因子 (NGF) は,グアニンヌクレオチド交換因子とGTPase活性化タンパク質 (GAP) の活動の両方を増加させ,Rasタンパク質を活性化します. NGF受容体システムはこれらの効果を強化し,Rasの活性化はこれらの調節タンパク質のバランスに依存することを示唆しています.

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