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Updated: Jan 22, 2026

Fusion of Secretory Vesicles with the Plasma Membrane
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T細胞受容体のトリガリングは,そのペプチド-MHCリガンドの寸法に決定的に依存しています

Kaushik Choudhuri1, David Wiseman, Marion H Brown

  • 1Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, UK.

Nature
|July 29, 2005
PubMed
まとめ

T細胞抗原受容体 (TCR) とペプチド-MHC (pMHC) 複合体の大きさは,T細胞活性化に極めて重要です. この複合体を延長すると,T細胞のトリガリングが減り,免疫信号伝達における分子サイズの重要性を強調する.

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