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Updated: Aug 16, 2026

A Simple Bioassay for the Evaluation of Vascular Endothelial Growth Factors
09:04

A Simple Bioassay for the Evaluation of Vascular Endothelial Growth Factors

Published on: March 15, 2016

生物学的活性ホルボールエステルは,表皮成長因子膜受容体の親和性を特異的に変化させます

M Shoyab, J E De Larco, G J Todaro

    Nature
    |May 31, 1979
    PubMed
    まとめ

    12-O-テトラデカノイル-ホルボル-13-アセテート (TPA) は,細胞内の表皮成長因子 (EGF) 受容体結合親和性に影響を及ぼします. このホルボールのエステルは,受容体数を変化させることなく,EGF受容体相互作用に影響を与え,細胞の成長と腫瘍の促進に影響を与えます.

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