標的細胞におけるウイルスタンパク質合成の欠如におけるT細胞細胞毒性

U Koszinowski1, M J Gething, M Waterfield

  • 1ICRF Tumour Immunology Unit, Department of Zoology, University College London, UK.

Nature
|May 12, 1977
PubMed
まとめ

細胞毒性T細胞は,ウイルスの抗原をメジャー・ヒストコンパティビリティ・コンプレックス (MHC) 分子と関連付けることで,ウイルスに感染した細胞を認識します. この研究は,仙台ウイルスの封筒が細胞を直接改変し,内部ウイルスの改変を除いて,T細胞殺害のターゲットにすることができることを示しています.

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