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Updated: Jul 18, 2026

Modeling an Enzyme Active Site using Molecular Visualization Freeware
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タンパク質チロシンフォスファタゼ1B (PTP1B) の活性に対する酸化還元調節のための化学モデル

Santhosh Sivaramakrishnan1, Kripa Keerthi, Kent S Gates

  • 1Departments of Chemistry and Biochemistry, University of Missouri, Columbia, MO 65211, USA.

Journal of the American Chemical Society
|August 4, 2005
PubMed
まとめ

過酸化水素 (H2O2) は,タンパク質のリン酸相を調節する. 新しいモデルは,タンパク質チロシンファスファタゼ1Bの酸化不活性化がクロスリンクを形成することを明らかにし,細胞における一般的なリドックススイッチングメカニズムを示唆しています.

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