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Updated: Jul 19, 2026

Analyzing and Building Nucleic Acid Structures with 3DNA
16:24

Analyzing and Building Nucleic Acid Structures with 3DNA

Published on: April 26, 2013

チオステプトンの全合成. レトロ合成分析と,重要な構成要素の構築

K C Nicolaou1, Brian S Safina, Mark Zak

  • 1Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA. kcn@scripps.edu

Journal of the American Chemical Society
|August 4, 2005
PubMed
まとめ

この研究は,複雑なチオペプチド抗生物質であるチオストレプトンの合成の最初の段階を詳細に説明しています. 重要な中間物質はステレオ選択的に構築され,デヒドロピペリジンのコアを合成し,ペプチド断片に結合させるという課題を克服しました.

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