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Updated: Jul 10, 2026

Techniques to Induce and Quantify Cellular Senescence
06:51

Techniques to Induce and Quantify Cellular Senescence

Published on: May 1, 2017

BRAFE600に関連した老化のようなヒトナエビの細胞サイクル停止

Chrysiis Michaloglou1, Liesbeth C W Vredeveld, Maria S Soengas

  • 1Division of Molecular Genetics, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands.

Nature
|August 5, 2005
PubMed
まとめ

メラノサイトにおけるBRAF (V600E) 変異によって引き起こされる腫瘍遺伝子誘発の衰老は,腫瘍の成長を防ぐ保護メカニズムとして作用します. この研究は,腫瘍遺伝子の誘発による衰老が,ヒトの体内で観察される生理学的プロセスであることを確認しています.

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Induction and Validation of Cellular Senescence in Primary Human Cells08:18

Induction and Validation of Cellular Senescence in Primary Human Cells

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SA-β-Galactosidase-Based Screening Assay for the Identification of Senotherapeutic Drugs07:39

SA-β-Galactosidase-Based Screening Assay for the Identification of Senotherapeutic Drugs

Published on: June 28, 2019

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