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Updated: Jul 26, 2026

Preparation and Fractionation of Xenopus laevis Egg Extracts
07:45

Preparation and Fractionation of Xenopus laevis Egg Extracts

Published on: August 27, 2008

細胞表面β-アミロイド前駆体タンパク質をリソソームに標的化:アミロイドを含む断片に代替処理

C Haass1, E H Koo, A Mellon

  • 1Department of Neurology, Harvard Medical School, Brigham and Women's Hospital, Boston, Massachusetts 02115.

Nature
|June 11, 1992
PubMed
まとめ

アルツハイマー病は,アミロイドβ-ペプチドの蓄積を伴う. この研究は,リゾソームにおけるβ-アミロイド前駆体タンパク質 (β-APP) 処理のための第2の経路を明らかにし,潜在的にアルツハイマー病に関連したアミロイド断片を生成します.

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