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Updated: Jul 11, 2026

Characterization of Multi-subunit Protein Complexes of Human MxA Using Non-denaturing Polyacrylamide Gel-electrophoresis
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Characterization of Multi-subunit Protein Complexes of Human MxA Using Non-denaturing Polyacrylamide Gel-electrophoresis

Published on: October 28, 2016

ヒトARF6-GTPによるコレラ毒素の活性化の構造的基礎

Claire J O'Neal1, Michael G Jobling, Randall K Holmes

  • 1Department of Chemistry, University of Washington, Seattle, WA 98195, USA.

Science (New York, N.Y.)
|August 16, 2005
PubMed
まとめ

コレラ毒素は,ヒトのADP-リボシライゼーション因子 (ARF) を悪用して病気を引き起こす. 構造的な研究は,ARFの結合が毒素をどのように変化させ,重要なシグナル伝達タンパク質を活性化させ,下痢を引き起こすかを明らかにしています.

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