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Updated: Jul 5, 2026

Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides (CHIPS)
06:34

Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides (CHIPS)

Published on: June 20, 2014

エナチオセレクティブの有機触媒性アリルアミネーション

Thomas B Poulsen1, Carlos Alemparte, Karl Anker Jørgensen

  • 1The Danish National Research Foundation: Center for Catalysis, Department of Chemistry, Aarhus University, DK-8000 Aarhus C, Denmark.

Journal of the American Chemical Society
|August 18, 2005
PubMed
まとめ

新しい有機触媒法により,高度にエナチオセレクティブなアリルアミネーションが可能になる. この効率的な戦略は,キナクリンやクロロキンなどの生物活性化合物を合成するための貴重なキラル構成要素を生み出します.

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Introduction
One of the convenient methods for the preparation of aldehydes and ketones is via hydration of alkynes. Hydroboration-oxidation of alkynes is an indirect hydration reaction in which an alkyne is treated with borane followed by oxidation with alkaline peroxide to form an enol that rapidly converts into an aldehyde or a ketone. Terminal alkynes form aldehydes, whereas internal alkynes give ketones as the final product.
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Heterogeneous Catalysis

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