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Updated: Jun 19, 2026

Isolation and Differentiation of Stromal Vascular Cells to Beige/Brite Cells
07:22

Isolation and Differentiation of Stromal Vascular Cells to Beige/Brite Cells

Published on: March 28, 2013

SUMOylationに依存する経路は,PPAR-gammaによって炎症反応遺伝子のトランスプレッションを媒介する

Gabriel Pascual1, Amy L Fong, Sumito Ogawa

  • 1Department of Cellular and Molecular Medicine, University of California San Diego, 9500 Gilman Drive, La Jolla, California 92093, USA.

Nature
|August 30, 2005
PubMed
まとめ

ペロキシソーム増殖器活性化受容体-ガンマ (PPAR-ガンマ) アゴニストは,基因プロモーターを標的とするコアプレッサーを勧誘することによって,炎症性遺伝子を抑制する. このメカニズムは,PPAR-ガンマが活性化剤から抑制剤に変換され,免疫とホメオスタシスに影響を及ぼす方法を説明します.

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