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Updated: Jul 13, 2026

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Free Radicals in Chemical Biology: from Chemical Behavior to Biomarker Development
Published on: April 15, 2013
仕事に"縛られる":自由ホルモン仮説が再考された
1Burns and Allen Research Institute, Cedars-Sinai Medical Center, David Geffen School of Medicine at UCLA, University of California, Los angeles, CA 90048, USA.
Cell
|September 7, 2005
まとめ
細胞の吸収に関与する受容体であるメガリンが欠けている動物は,性ステロイドホルモンに対する抵抗性を示す. これは,メガリンがこれらの重要なホルモンの効果を媒介する上で重要な役割を果たしていることを示唆しています.
科学分野:
- エンドクリノロジー エンドクリノロジー
- 細胞生物学 細胞生物学
- 分子生物学は分子生物学である.
背景:
- メガリンは,低密度リポプロテイン受容体関連タンパク質 (LRP) 家族に属する細胞表面受容体です.
- LRPファミリーのメンバーは,様々な細胞外リガンドのための内細胞受容体として機能します.
- この研究では,性ステロイドホルモンの作用に関連してメガリンの生理学的役割を調査しています.
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