運動テストとフレミングハムリスクスコアによる無症状の個体における強化されたリスク評価
Samia Mora1, Rita F Redberg, A Richey Sharrett
1Center for Cardiovascular Disease Prevention, Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical Schoo, Boston, MA, USA. smora2@partners.org
Circulation
|September 8, 2005
まとめ
フレミングハムリスクスコアに運動能力と心拍数回復を加えると,無症状の個体における心血管疾患のリスク予測が著しく改善されます. これらの測定は,FRSだけで逃した高リスク患者を特定し,臨床評価を強化します.
科学分野:
- 心臓病学 心臓病学
- 予防医学は,予防的な医療です.
- 運動生理学 運動生理学
背景:
- 現在のガイドラインでは,無症状の個体における心血管リスク評価のために,フレーミングハムリスクスコア (FRS) を使用しています.
- この研究では,運動テストの対策がFRSの精度を高めることができるかどうかを調査しています.
研究 の 目的:
- 運動能力 (MET) と心拍数回復 (HRR) が,FRSを超える心血管疾患 (CVD) のリスク予測を改善するかどうかを判断する.
- FRSとMETとHRRの組み合わせた予測値を評価する.
主な方法:
- ベースラインのトレッドミールテストを受けた無症状の6126人の20年間のフォローアップ.
- 心血管疾患 (CVD) 死因の分析,FRS,MET,HRRとの関係.
- 調整された危険比率は,独立した予測値と組み合わせた予測値を評価するために計算されました.
主要な成果:
- 低METまたはHRRは,CVD死亡の91%を占める個人を特定しました.
- 低METとHRRを組み合わせると,高いMET/高いHRRと比較して,心血管疾患による死亡リスクが著しく増加した (例えば,女性:8.51,男性:3.53).
- この組み合わせた評価は,FRSだけで見逃された高リスクの個人を特定し,特に中等リスクのグループで特定しました.
結論:
- 運動テスト (METsとHRR) は,無症状の個体におけるリスク評価のためのFRSの貴重な補足です.
- 特に,FRS 6%~19%の女性,FRS 10%~19%の男性に恩恵を与えています.
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