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Updated: Jul 13, 2026

Yeast As a Chassis for Developing Functional Assays to Study Human P53
14:57

Yeast As a Chassis for Developing Functional Assays to Study Human P53

Published on: August 4, 2019

野生型のp53は,体外での転写を活性化する

G Farmer1, J Bargonetti, H Zhu

  • 1Department of Biological Sciences, Columbia University, New York 10027.

Nature
|July 2, 1992
PubMed
まとめ

野生型のp53タンパク質は,細胞成長の調節に不可欠な機能である転写を直接活性化します. 変異したp53タンパク質とSV40大T抗原は,この転写活性化を阻害することができます.

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