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Updated: Jul 10, 2026

In vitro Synthesis of Native, Fibrous Long Spacing and Segmental Long Spacing Collagen
07:54

In vitro Synthesis of Native, Fibrous Long Spacing and Segmental Long Spacing Collagen

Published on: September 20, 2012

リボヌクレアゼAのアミロイド状の繊維は,三次元ドメイン交換とネイティブのような構造を持つ

Shilpa Sambashivan1, Yanshun Liu, Michael R Sawaya

  • 1Howard Hughes Medical Institute, UCLA-DOE Institute for Genomics and Proteomics, Box 951570, UCLA, Los Angeles, California 90095-1570, USA.

Nature
|September 9, 2005
PubMed
まとめ

研究者は,RNase Aからアミロイドのような繊維を設計し,これらのタンパク質集積がネイティブのような構造と酵素活性を維持できることを明らかにしました. これは,繊維の形成のジッパー-脊椎モデルを支持しています.

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