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Updated: Jul 5, 2026

High-resolution Respirometry to Measure Mitochondrial Function of Intact Beta Cells in the Presence of Natural Compounds
12:32

High-resolution Respirometry to Measure Mitochondrial Function of Intact Beta Cells in the Presence of Natural Compounds

Published on: January 23, 2018

CREBのコアクティベーターであるTORC2は,断食中のグルコース代謝の重要な調節因子である

Seung-Hoi Koo1, Lawrence Flechner, Ling Qi

  • 1Peptide Biology Laboratories, Salk Institute for Biological Studies, 10010 N Torrey Pines Rd, La Jolla, California 92037-1002, USA.

Nature
|September 9, 2005
PubMed
まとめ

ホルモンとエネルギー信号は,TORC2 (規制されたCREB活動2のトランスデューサー) に収束し,肝臓のグルコース生成を制御します. AMPKの活性化は,TORC2の核の侵入を阻害することによってグルコネオゲネシスを阻害し,2型糖尿病の潜在的な治療法を提供します.

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