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Updated: Jun 27, 2026

Visualization of DNA Replication in the Vertebrate Model System DT40 using the DNA Fiber Technique
07:18

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Published on: October 27, 2011

CDKは,Cdc6をAPC/C依存型タンパク質分解から保護することによって,ヒト細胞におけるDNA複製の起源許可を促進する

Niels Mailand1, John F X Diffley

  • 1Cancer Research UK London Research Institute, Clare Hall Laboratories, Hertfordshire, United Kingdom.

Cell
|September 13, 2005
PubMed
まとめ

サイクリン依存キナーゼ (CDK) は通常,DNA複製の許可を防ぐが,ここではCdc6タンパク質を安定させる. この安定化は,細胞分裂前の重要なステップである,複製前の複合体の組み立てを可能にします.

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