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Updated: Jul 6, 2026

Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation
08:43

Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation

Published on: May 31, 2016

アトルバスタチンは,Lrp5受容体経路経由で大動脈弁の高コレステロール血症に起因する化を抑制します

Nalini M Rajamannan1, Malayannan Subramaniam, Frank Caira

  • 1Division of Cardiology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA. n-rajamannan@northwestern.edu

Circulation
|September 15, 2005
PubMed
まとめ

アトルバスタチンは,Lrp5/β-カタニン経路を阻害することによって,高コレステロール血症における大動脈弁の結石化を減少させます. この経路は,弁膜性心疾患における細胞増殖と骨形成に不可欠である.

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