慢性性不全性ミトラル吐症患者の環状幾何学: 3次元磁気共鳴画像の研究

Shuichiro Kaji¹, Michihiro Nasu, Atsushi Yamamuro

¹Division of Cardiology, Department of Cardiovascular Surgery, Kobe General Hospital, 4-6, Minatojima-nakamachi, Kobe, 650-0046, Japan. skaji@kcgh.gr.jp

Circulation

|September 15, 2005

まとめ

慢性性不全性ミトラル反発症 (CIMR) の患者は,拡大および平らなミトラルアヌリウムを示します. このミトラアヌルスの幾何学的な変化は,CIMRの発達を理解するための鍵です.

科学分野:

心臓病学心臓病学
心臓画像検査 (Cardiac Imaging) について
構造的な心疾患である.

背景:

動物の研究は,環状リモデリングが慢性性イシュケミックミトラル吐 (CIMR) に寄与することを示唆しています.
CIMRにおけるミトラの環状幾何学に関するヒトのデータは限られている.
精密な3D幾何学の理解は,外科的介入に不可欠です.

研究の目的:

CIMR患者の3Dミトラルの環状幾何学を解明する.
ミトラル環状の寸法とCIMRの重度との関係を調査する.

主な方法:

心臓MRIは,前回の心筋梗塞を患った38人の患者を研究するために使用されました.
mitra annulus と subvalvular apparatus の 3D 再構築が行われました.
患者は,エコーカルディオグラフィックによるミトラル逆流症の重症度に基づいて分類された.

主要な成果:

CIMRの患者は,セプト・ラテラルおよびコンシューラ・コンシューラ環状直径が著しく大きくなりました.
繊維状アヌルスの長さは,CIMR患者でより大きかった.
CIMR患者のミトラアヌリは,円形の高度が低く,高度と幅の比率が低く,より平らでした.

結論:

CIMRの患者には,ミトラル環状のサイズが拡大している.
平らなミトラル環状のサドル形と三角間距離の増加はCIMRの特徴です.
これらの幾何学的変化は,慢性発血性ミトラル吐症の病原性に関与しています.

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