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Updated: Jul 6, 2026

High-throughput Screening for Protein-based Inheritance in S. cerevisiae
08:12

High-throughput Screening for Protein-based Inheritance in S. cerevisiae

Published on: August 8, 2017

不活性なプロカリオットSODホモログから,サイト誘導型変異変異を通して活性タンパク質に

Lucia Banci1, Manuela Benvenuti, Ivano Bertini

  • 1Department of Chemistry and Centro Risonanze Magnetiche, University of Florence, 50019 Sesto Fiorentino, Italy.

Journal of the American Chemical Society
|September 22, 2005
PubMed
まとめ

研究者は,銅リガンドを再導入することによって,バチルス・サブティリスのSODのようなタンパク質を設計した. 改変された酵素は部分的な活性を示し,スーパーオキシドディスミュータゼ機能に対する特定の金属の調整の重要性を強調した.

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