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インスリンは,アディポサイト内のタンパク質キナーゼAへのβ-アドレナージ信号伝達を妨害する

Jin Zhang1, Christopher J Hupfeld, Susan S Taylor

  • 1Department of Pharmacology, University of California at San Diego, La Jolla, California 92093, USA.

Nature
|September 24, 2005
PubMed
まとめ

慢性的に高いインスリンレベルは,タンパク質キナーゼA (PKA) 構造を破壊することによって,逆説的にアディポサイトにおけるβ-アドレネルジック受容体シグナル伝達を強化し,新しいクロストークメカニズムを明らかにします.

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