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Updated: Jul 30, 2026

Anti-virulent Disruption of Pathogenic Biofilms using Engineered Quorum-quenching Lactonases
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カンジダ・アンタルティカ菌のリパゼBの触媒活性を円形パルミュテーションによって改善する

Zhen Qian1, Stefan Lutz

  • 1Department of Chemistry, Emory University, Atlanta, Georgia 30322, USA.

Journal of the American Chemical Society
|September 30, 2005
PubMed
まとめ

循環変異工学により,カンジダ・アンタルティカ・リパゼB (CALB) の63の機能的な変種が作成されました. 多くの変種が活性性を維持または改善し,非自然な基質のための新しいバイオカタリストの開発のためのこの方法を検証しました.

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