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Updated: Jul 16, 2026

Immobilization of Multi-biocatalysts in Alginate Beads for Cofactor Regeneration and Improved Reusability
09:27

Immobilization of Multi-biocatalysts in Alginate Beads for Cofactor Regeneration and Improved Reusability

Published on: April 22, 2016

酵素の再設計: 2つの変異が協力して,サイクロアルテノール合成酵素を正確なラノステロール合成酵素に変換します

Silvia Lodeiro1, Tanja Schulz-Gasch, Seiichi P T Matsuda

  • 1Department of Chemistry and Department of Biochemistry and Cell Biology, Rice University, Houston, TX 77005, USA.

Journal of the American Chemical Society
|October 13, 2005
PubMed
まとめ

研究者は,サイクロアルテノール合成酵素を高度に特異的なラノステロール合成酵素に改造した. この酵素再設計は,極性およびステリックの修正を組み合わせることで,ラノステロールの生産に99%の精度を達成しました.

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