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Updated: Jul 8, 2026

Split-and-pool Synthesis and Characterization of Peptide Tertiary Amide Library
13:37

Split-and-pool Synthesis and Characterization of Peptide Tertiary Amide Library

Published on: June 20, 2014

塩素-アル複合体によって触媒化されたアルファ,ベータ不飽和イミドへのエナチオセレクティブ・マイケル添加物

Mark S Taylor1, Eric N Jacobsen

  • 1Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, Massachusetts 02138, USA.

Journal of the American Chemical Society
|October 14, 2005
PubMed
まとめ

新しい (サレン) アルミニウム複合体は,結合添加反応を効率的に触媒化し,貴重な多機能化合物を生み出します. この方法は, (-) - パロキセチンへの経路を含む,エナチオメリックに濃縮されたピペリジンの非対称合成を可能にします.

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Acid-Catalyzed α-Halogenation of Aldehydes and Ketones

By replacing an α-hydrogen with a halogen, acid-catalyzed α-halogenation of aldehydes or ketones yields a monohalogenated product
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