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Updated: Jun 20, 2026

Improved Preparation and Preservation of Hippocampal Mouse Slices for a Very Stable and Reproducible Recording of Long-term Potentiation
09:39

Improved Preparation and Preservation of Hippocampal Mouse Slices for a Very Stable and Reproducible Recording of Long-term Potentiation

Published on: June 26, 2013

コカインの繰り返し暴露は,中脳ドーパミンニューロンにおけるLTP誘導を促進します

Qing-song Liu1, Lu Pu, Mu-ming Poo

  • 1Division of Neurobiology, Department of Molecular and Cell Biology, Helen Wills Neuroscience Institute, University of California, Berkeley, California 94720, USA. qsliu@berkeley.edu

Nature
|October 14, 2005
PubMed
まとめ

コカインを繰り返し摂取すると,GABA (A) 受容体の阻害を減らし,腹部帯膜領域 (VTA) のドーパミンニューロンにおけるシナプス可塑性を高めます. これにより,長期増強 (LTP) が促進され,薬物関連記憶形成に潜在的に役立ちます.

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