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Updated: Jul 5, 2026

Visualization of ATP Synthase Dimers in Mitochondria by Electron Cryo-tomography
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F1-ATPaseによるATPの合成と水解のための構造ベースのモデル

Yi Qin Gao1, Wei Yang, Martin Karplus

  • 1Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, USA.

Cell
|October 22, 2005
PubMed
まとめ

ナノスケールの回転モーターであるF1-ATPaseは,ATPを効率的に合成します. そのメカニズムは,ATPの合成と水解のための明確なタンパク質構成を含み,細胞のATPレベルがATPの機能を抑制しない理由を説明します.

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If one phosphate group is removed, a molecule of ADP—adenosine diphosphate—remains, along with inorganic phosphate. ADP can be further hydrolyzed to AMP—adenosine monophosphate—by the removal of a second...
Hydrolysis of ATP01:08

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The bonds of adenosine triphosphate (ATP) can be broken through the addition of water, releasing one or two phosphate groups in an exergonic process called hydrolysis. This reaction liberates the energy in the bonds for use in the cell—for instance, to synthesize proteins from amino acids.
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