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Updated: Jul 6, 2026

The Logic, Experimental Steps, and Potential of Heterologous Natural Product Biosynthesis Featuring the Complex Antibiotic Erythromycin A Produced Through E. coli
10:41

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ラクチシン481合成酵素は,ランチビオティック生産中にその基質をリン酸化します

Champak Chatterjee1, Leah M Miller, Yong L Leung

  • 1Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.

Journal of the American Chemical Society
|November 3, 2005
PubMed
まとめ

ラクチシン481合成酵素 (LctM) はATPを使用してセリン/スレオニン残基をリン酸化し,抗生物質合成を開始します. このリン酸化段階は,酵素にとって極めて重要です.

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